For more information, see the documentation below.
Transportable hypothermic machine perfusion for donor kidney
Hypothermic, Oxygenated, Machine, Perfusion, Kidney
WAVES is used for the pulsatile hypothermic machine perfusion of donor kidneys for preservation, transportation, and eventual transplantation into a recipient.
WAVES is a two part system consisting of a control unit and a single use disposable cassette which contains the kidney and the machine preservation solution.
WAVES provides a sealed & insulated environment where a solution is pumped through the kidney at cold temperatures while the organ is being preserved outside the body. WAVES is portable allowing an organ to be perfused from time of recovery until transplantation. It is designed to travel unaccompanied by land or air, safely transporting the kidney across town or between countries (read instruction for use for complete details).
While the kidney is being perfused, WAVES records data on temperature, flow, pressure, and Renal Resistance (RR) every minute, offering clinicians additional data to evaluate the organ.
- Physiologic
- Arterial pressure waveform
- Active oxygenation
- Convenient
- Touchscreen & Guided Interface
- Remote monitoring of perfusion
- Safe transport
- Unaccompanied transport
- Insulated protection
WAVES System
Includes 24/7 hotline technical support, warranty and maintenance services (details by country, see contact)
WAVES Control Unit
WAVES Transport Bag
Disposable Cassettes
Disposable Clamp
Disposable Cannula
Disposable Trident Artery Cannula
Preparing the system
Ensure all necessary equipment and supplies are ready to go to the recovery location
Entering perfusion information
Use the interface to enter perfusion information
Activating the cooling pump
WAVES provides a regulated cold environment for the explanted kidney. The cold source used to create hypothermic conditions consists in a 5 liters water-and-ice slush, inserted in the reservoir.
Placing the cassette
The cassette and the unit are designed to be automatically aligned. The cassette only fits into the device in one position. Three latches allows to secure the cassette.
Loading the perfusate circuit
Add 1 liter of solution approved for kidney machine perfusion
Activating the hypothermic perfusate perfusion
WAVES cools the perfusate at about 5°C. The cold environment is automatically regulated by the system.
Cannulating the kidney – with patch reprocessing Clamp
Use the reprocessing clamp for kidney with an aortic patch
Cannulating the kidney with Patch Disposable Clamp
Use the disposable clamp for kidney with an aortic patch
Cannulating the kidney with Patch CHO Clamp
Use the disposable clamp for kidney with an aortic patch
Cannulating the kidney with Patch Disposable (Fixed Jaw) Clamp
Use the disposable cannula for kidney without aortic patch
Cannulating the kidney without Patch Disposable Cannula
Use the disposable cannula for kidney without aortic patch
Cannulating the kidney without Patch Reprocessing Cannula
Use the disposable cannula for kidney without aortic patch
Cannulating the kidney with multiple vessels
Use the disposable trident for kidney with multiple vessels
Placing the sterile drape
Use the disposable sterile drape to create an aseptic operating environment on the unit
Placing the kidney
The cassette is equipped with a removable platform offering two positions. The Up or benching position permits the user to have easy access to the kidney, particularly during placement for perfusion. The Down or perfusion position must be used during the perfusion.
Placing the kidney – with multiple vessels
Use the disposable trident for kidney with multiple vessels
Setting perfusion pressure – automatic mode
With the automatic mode the perfusion pressure is maintained at a set pressure during 6 hours.
Setting perfusion pressure – manual mode
With manual mode the user adjusts continuously the perfusion pressure during the procedure.
Closing the system
Once closed the system houses the organ cassette safely, in sealed and sterile environment for the transport.
Checking perfusion parameters
The interface allows the user to monitor continuously systolic, mean, and diastolic pressure, flow, temperature and renal resistance.
Changing perfusion mode
The perfusion mode can be changed from automatic to manual and vice versa at any time during the procedure.
Checking batteries charge
Battery operation lasts up to 24 hours with four fully charged batteries.
Locking/unlocking screen
Screen is to be locked for transport to prevent any unintentional operation through the interface.
Setting system for transport
Lock screen and place the WAVES system into the transport bag
Ending perfusion
Perfusion data (temperature, flow, pressure, and Renal Resistance) are automatically saved at the end of the perfusion procedure.
Removing the kidney
Use aseptic techniques for removing the kidney
Visualizing the perfusion data
Navigate the user friendly interface to visualize the perfusion data
Transferring the perfusion data
The WAVES control unit has a USB port for data transfer and storage onto a flash drive on the back of the unit.
Network the perfusion data
The WAVES system permits the user to view the current perfusion data on a network or smartphone when the unit is properly connected to a network. The WAVES has an Ethernet port on the back of the unit for network connection.
Draining the ice reservoir
WAVES provides a convenient automated draining of the slush water-ice after perfusion.
Cleaning up after perfusion
Bleach solution in reservoir, drain, wipe of the reservoir, and dry. Spray and wipe of the unit
Swapping batteries
WAVES draws power from one battery at a time, so you may swap out depleted batteries for fully charged ones without interrupting perfusion.
Retrieving a perfusate sample
Attach a syringe to remove a perfusate sample for testing purposes
Injecting medication into sample port
Attach a syringe to inject medication into the perfusate
Contact us for more information